AnestAssist PK/PD

Palma Healthcare Systems LLC

AnestAssist PK/PD is an educational tool used for understanding and visualizing the pharmacokinetics; pharmacodynamics; and interactions of commonly used anesthetic drugs. Anesthesiologists; CRNA’s; veterinarians; and other clinicians involved with anesthesiology; from residents to the very experienced; will find AnestAssist a valuable tool for understanding rational dosing strategies tailored to individual patients. Mathematical models; published in peer reviewed anesthesia journals (see www.palmamhealthcare.com); which take into account patient weight; age; and gender; are used to estimate and chart: Plasma Concentration (IV drugs) Alveolar Concentration (Inhaled agents) Effect Site Concentration Probability of Effect (individual and combined drug interactions) Analgesia: No response to laryngoscopy Sedation: OAA/S < 2 NMB: T1/T0=50% IV drugs included: Propofol; Remifentanil; Fentanyl; Alfentanil; Sufentanil; Dexmedetomidine; Ketamine; Lidocaine; Morphine; Midazolam; Atracurium; Cisatracurium; Rocuronium; and Vecuronium. Inhaled agents included: Sevoflurane; Isoflurane; Desflurane; Enflurane; Halothane; and Nitrous Oxide. Interactions modeled: Propofol; Sevoflurane; or Isoflurane with any combination of Remifentanil; Fentanyl; Alfentanil; or Sufentanil. Users can add drugs and PK/PD model parameters to the system in addition to those included above. Real-Time Case Capture: Drug entry system facilitates recording drugs administered real-time or retrospectively from intra-operative record. Save to Case Library for later review. Case Library: Save actual cases or design and add your own cases to the library to record and demonstrate dosing strategies for a variety of patient types and drugs. AnestAssist runs an enhanced user interface full screen natively on the iPad and in standard mode on the iPhone/iPod. The core functionality is the same on both. Please see www.palmahealthcare.com for detailed information. For Educational Use Only